Scientist

  • location: Boston, MA
  • type: Permanent
  • salary: $110,000 - $130,000 per year

job description

Scientist

Job Title: Cell Biologist / Oncolgy Drug Development Project Leader

Position Description

  • Seeking an independent, highly motivated Cell Biologist with extensive Oncology experience to lead one or more projects.
  • The successful candidate will design, perform and analyze experiments using primary tumor samples to identify sensitive sub-populations of patients, validate targets, and help expand our platform.
  • An in-depth knowledge of oncological pathways is preferred; experience working with primary biopsies and/or HTS of samples is desirable.
  • The scientist must have a proven track record of research contributions and work productively in teams.
Position Responsibilities

  • Design and execution of assays using primary human biopsies
  • Characterize the response to drugs using biochemical and imaging techniques
  • Establish techniques for limited propagation of primary samples for use in proprietary functional assays
  • Perform flow cytometry assays to measure tissue-specific markers
  • Analyze large matrixed data sets including functional responses and genomic data (e.g. using Spotfire)
  • Establish biomarker assays for pre-clinical and clinical use
  • Design PK/PD and in vivo POC experiments
  • Intellectual contributions to direction of projects and evaluation of new targets
  • Project leadership including establishing goals and working within budgets and timelines
Position Requirements

  • PhD in a biological discipline (e.g. cell biology, genomics, molecular biology etc.)
  • Minimum of 5 years' experience
  • Proven track record of driving a significant scientific project to success
  • Strong knowledge in oncology
  • Previous experience with primary human samples is desirable
  • Previous project leadership experience is a plus

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