Lab Technician

  • location: Collegeville, PA
  • type: Contract
  • salary: $18.05 - $21.24 per hour

job description

Lab Technician

Job Title: Laboratory Technician - Level 1 US

Job Summary

  • An exciting opportunity is available to participate in operation of the Codexis CodeEvolverĀ® enzyme evolution platform.
  • This platform technology enables use of enzymes and cells in small and large molecule drug manufacturing.
  • The primary focus of the role is to support the directed evolution platform by participating in the construction, expression, and NGS sequencing of enzyme libraries.
  • The successful candidate would participate on an interdisciplinary team tasked with providing fit for purpose enzymes to chemistry project teams
Job Responsibilities

  • Execution of all elements of an NGS project, from amplicon preparation to data analysis
  • Optimize 96-well library preparation protocols
  • Utilize high throughput cloning technology to construct mutant enzyme libraries
  • Manipulate large-scale datasets using MS Excel and equipment interfacing programs.
  • Optimize 96-well protein expression in various host organisms
  • Liaise with scientists & external collaborators at all levels
  • Generate conclusion reports, present data in team meetings & participate in writing of abstracts & publications
  • Conduct scientific work programs and make contributions both independently or as a member of a team with other R&D staff
  • Work through problems logically and apply innovative solutions
  • Adopt new technologies and apply them to project work
  • Maintain customer focus, motivate self, and demonstrate a high degree of urgency
  • Use scientific literature and database resources in the execution of project related work
  • Exhibit flexibility, being open to new ways of working
Education & Qualifications

Basic Qualifications:

  • BS with 1-3 years relevant experience in Molecular Biology or related field
  • Experience with modern molecular biology techniques, including PCR, digest, ligation, and gel electrophoresis
  • Experience in protein expression
  • Awareness of next-generation DNA sequencing technologies and library preparation protocols
  • Demonstrated ability to work in multi-disciplinary teams, displaying excellent interpersonal, organizational, and communication skills
Preferred Qualifications:

  • Familiarity with high-through put liquid handling and automation equipment
  • Experience optimizing enzyme expression, especially for high-throughput applications
  • Knowledge of standard bioinformatics and structural analysis tools
  • Understanding of directed evolution approaches including both random and rational methods
  • Awareness of synthetic biology and enzyme engineering techniques
Benefits

  • Medical, Dental, and Vision Insurance
  • 401K Plan with Company Match
  • Life and AD&D Insurance

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