Scientist III (R&D)

  • location: Cambridge, MA
  • type: Contract
  • salary: $44.75 - $52.65 per hour
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job description

Scientist III (R&D)

job summary:
As the world's largest staffing and recruitment agency in the world, we can commit to find you the perfect role that gives you the opportunity to learn and grow in the life sciences arena. Utilizing a recruiter for your job search gives you access to a large network of top employers as well as detailed information about hundreds of positions. With a hefty goal of discovering medical breakthroughs to treat devastating neurological ailments, our partner is focused on furthering research and finding ways to improve our healthcare system. You can feel secure in the fact that you will be paving the way to life changing practices when you work for this well-known team!

 
location: Cambridge, Massachusetts
job type: Contract
salary: $44.75 - 52.65 per hour
work hours: 9 to 5
education: Doctorate
 
responsibilities:
Alzheimer's Disease and Dementia Research Unit (AD&D RU) at the company seeks an accomplished and driven scientist to join their team in a contract position. The AD&D RU is focused on leveraging genetics and human biology for developing and delivering innovative therapeutic intervention strategies for AD and other dementias.

The candidate will be a part of a fast-faced and motivated drug discovery group and will be directly contributing to drug discovery for AD.

The Alzheimer's Disease & Dementia Research Unit at the company is seeking a highly talented and motivated scientist to join a fast-paced and driven drug discovery group that is focused on the identification and rapid progression of novel therapeutics for Alzheimer's disease in the role of a Contract Position. The candidate will be responsible for:

  • Developing and executing new assays with focus on lipid biology and neurovascular biology in Alzheimer's disease.
  • Independently designing and executing in vitro and in vivo biology experiments, including mechanism of action studies for drug discovery programs.
  • Demonstrating scientific and technical leadership; and, be able to lead from the bench, generate high quality data, perform data analysis and interpretation, and present at team meetings while following high scientific rigor.
  • Working effectively and collaboratively with members of the group.
 
qualifications:
  • Ph.D. in neuroscience or biological sciences with a minimum of 4 years of post-doctoral training and 2 years of drug discovery experience in industry in neuroscience.
  • An in-depth, up-to-date knowledge of concepts and hands-on experience in cellular and molecular neuroscience and application in AD or other neurodegenerative diseases.
  • In-depth experience with cell culture including cell lines, primary tissue culture, and iPSC-derived culture with a strong focus on astrocytes and microglial systems.
  • In-depth expertise in biochemical techniques and technologies including immunoblotting, ELISA, MSD, FRET, luminescence, co-immunoprecipitation.
  • In-depth expertise in molecular biology techniques such as nucleic acid purification from mammalian cells and tissue (both gDNA and RNA), reverse transcription and qPCR.
  • Prior experience with in vivo pharmacology (must be willing to work with animals).
  • Experience with general microscopy, immunofluorescent staining, and high content imaging is a plus.
  • Experience with apoE, lipid biology and neurovascular biology is a plus.
  • Keen understanding of experimental design, underlying scientific principles, and the ability to rigorously analyze and document results.
  • Strong interpersonal and organizational skills, ability to work effectively in a collaborative environment, ability to clearly communicate results to a scientific audience and to maintain detailed written records.
  • Experience of independent research in a pharmaceutical/biotechnology industry or related setting.
  • Drug discovery experience in neuroscience.
 
skills: Biology, In Vitro, In Vivo
Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.

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