The Biotherapeutics and Genetic Medicine Group is seeking a highly motivated scientist for initiating the lentiviral delivery platform for gene therapy in a newly established Genetic Medicine team. The candidate will work collaboratively with cross-functional and therapeutic area teams to advance company's lentiviral gene therapy pipeline. The ideal candidate will have strong expertise and experience in lentivirus vector engineering, production, analytics and in vitro screening, as well as experience in managing CROs for lentiviral production.
location: Worcester, Massachusetts
job type: Contract
salary: $60 - 68 per hour
work hours: 9 to 5
education: Doctorate
responsibilities:
- Collaborate with cross-functional and therapeutic area teams to advance novel lentiviral vectors into pipeline
- Design and engineer lentiviral vectors and manage lentiviral production by leveraging internal and CRO resources.
- Help build and establish analytical and cell-based screening assays (e.g., p24, VCN, SupT1 titration, ELISA, qPCR, ddPCR, WES, FACS, and endotoxin assay)
- Maintain a comprehensive Electronic Lab Notebook documenting experiments
- Maintain a high level of productivity in the team with clear daily, detailed, and accurate documentation of experiments
- Author technical reports and protocols
- Understand and enforce company culture, teamwork, safety, appropriate handling of materials in an BSL2 environment
- Perform all activities in compliance with applicable regulations, Company's policies and guidelines
- Bring a "can do" spirit to work and deliver on other responsibilities as assigned
qualifications:
Required Qualifications:
- Ph.D. in biology or a relevant field with 5+ years of experience in lentiviral vector-based gene therapy in addition to post-doctoral experience; or MS with at least 10 years of relevant experience; industrial experience highly desired
- Strong expertise and experience in lentiviral vector design, engineering and production
- Experience in managing CROs for lentiviral production
- Experience in analytical and screening methods for characterization of lentiviral vector products
- Experience in CAR-T cell therapy
- Ability to work effectively in a highly collaborative and dynamic environment
- Excellent verbal and written communication skills
- Excellent organization and collaborative skills
- Detail oriented with a passion to deliver quality results
- Experience in in vivo lentiviral targeted delivery
skills: Cell Biology, Biology, GLP (Good Laboratory Practice), In Vitro
Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.
At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact HRsupport@randstadusa.com.
Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including: medical, prescription, dental, vision, AD&D, and life insurance offerings, short-term disability, and a 401K plan (all benefits are based on eligibility).
This posting is open for thirty (30) days.
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.