The Center for Technology & Innovation (CfTI) department is seeking a highly motivated hands-on Senior Scientist (Computational Biologist) with expertise in clinical bioinformatics, biomarker development, assay development, ML algorithms & data science, statistical modeling, handling clinical data sets and a background in biology and computational sciences. This is a high-visibility, individual contributor role preferring experience within matrix environments representing the function and requiring the development of methods to support the entirety of the clinical portfolio.
The ideal candidate is a strong R programmer with experience analyzing clinical biomarker data tied to efficacy and safety outcomes, and who enjoys collaborating closely with scientists to iterate on analyses and interpretations.
location: Telecommute
job type: Contract
salary: $35.00 - 49.20 per hour
work hours: 9 to 5
education: Doctorate
responsibilities:
- Perform exploratory and hypothesis-driven analyses of prostate cancer biomarker datasets, evaluating associations between baseline and on-treatment biomarkers and clinical efficacy and safety endpoints.
- Document, refactor, and write clean R code / tidyverse code to accomplish scientific objectives set by Precision Medicine and global development leadership
- Engage in scientific discussion and iteration with hiring manager and technical review SMEs to revise and improve code and analyses.
qualifications:
- Ability to translate biological and medical questions into analytical models providing actionable results
- Deep knowledge of prostate indications
- Programming experience in R & Python and familiarity with tidyverse principles
- Familiarity with assay development and qualification requirements for clinical trial support
- Ability to work in a highly matrixed environment and drive scientific and technical innovation collaboratively with other members of the group, as well as with Company research community
- Three or more years of relevant experience in the biotech or pharmaceutical industry
- Strong written and oral communication skills, self-motivation, independence, and leadership
- Ph.D. in Bioinformatics, Mathematics, Statistics, Computer Science, or a related quantitative field with 2+ years of experience; or a Master's degree with 5+ years of experience.
- Significant experience in bioinformatics, applied mathematics and/or statistics, including linear mixed effects models, to analyze multi-modal, multi-dimensional and large-scale biological data
- A working knowledge of platforms and readouts utilized for the assessment of clinical biomarkers including flow cytometry, IHC, NGS, immunoassays, imaging, and transcriptional profiling assays
- Advanced programming proficiency in R, specifically adhering to tidyverse principles and reproducible research workflows.
- Demonstrated experience in clinical bioinformatics or a clinical development environment, including a deep understanding of cancer biology.
- Strong command of statistical modeling, including linear mixed effects models and survival analysis.
- Specific therapeutic area expertise in prostate cancer or broader solid tumor indications.
- Working knowledge of Machine Learning (ML) and Artificial Intelligence (AI) applications within clinical trial settings.
- Familiarity with assay development and qualification requirements for clinical trial support.
- Previous experience operating within a highly matrixed biotechnology or pharmaceutical corporate environment.
skills: Oncology, Biology, R Language, Bayesian Statistics, Bioinformatics
Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.
At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact HRsupport@randstadusa.com.
Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including: medical, prescription, dental, vision, AD&D, and life insurance offerings, short-term disability, and a 401K plan (all benefits are based on eligibility).
This posting is open for thirty (30) days.
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Qualified applicants in San Francisco with criminal histories will be considered for employment in accordance with the San Francisco Fair Chance Ordinance.
Qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
We will consider for employment all qualified Applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance.
