The primary responsibilities of the Biophysical Assay Research Associate will include performing analytical method development and testing samples using Capillary Electrophoresis, SDS-PAGE, DLS, MALS, AUC, and other analytical tools; contributing to design and performing experiments with supervision as needed; completing assigned tasks within time frames with high quality; maintaining a well-documented record of activities in lab notebook and reports. The position level will commensurate with education and experience level. Additionally, the role includes regularly summarizing and presenting experimental results in lab meetings and responsible for generating reports. This role will be at our South San Francisco location.
location: South San Francisco, California
job type: Contract
salary: $30 - 33 per hour
work hours: 9 to 5
education: Bachelors
responsibilities:
- Conducting experiments to characterize adeno-associated viral nanoparticles for gene therapy products.
- Performing assays for particle/protein/DNA in multiple assays (Capillary Electrophoresis, SDS-PAGE, DLS, Western Blot, Light Obscuration, AUC, RP, SE - HPLC methods, etc.) to assist in evaluation of product characterization, including but not limited to: process change, formulation study, stability study using statistical methods as needed, following SOPs and execute experiments according to guidelines.
- Developing new assays and transfer to QC, Process Development, and Research.
- Developing new analytical tools to characterize adeno associated viral nanoparticles for gene therapy products
- Participating in writing, reviewing, and editing experimental procedures and reports
- Maintaining accurate records of all analytical development activities timely
- Analyzing and determining the applicability of laboratory data to draw conclusions and to make appropriate recommendations
qualifications:
Required
- Bachelor of Science with 2+ years of experience working in a pharmaceutical or biotech company and with the requisite years' of experience employing the skills listed in the job description (for each level) performing multiple assays for bioproducts.
- Successful experience operating electrophoresis (CE, SDS-PAGE, alkaline gel, etc.), light scattering (DLS, MALS, etc.), UV/Vis spectrophotometry, or other technologies for protein/DNA-based product development.
- Strong knowledge and deep understanding of protein and DNA chemistry.
- Knowledge and proven experience in protein/DNA-based product development and characterization.
- Knowledge and expertise in principles and practice of current Good Manufacturing Practices (cGMP).
- Proficient in Microsoft Office to include Excel, PowerPoint, and Word.
- Experience with recording experiments in electronic lab notebooks.
- Demonstrated verbal and written skills in technical reports and documents.
- Positive, professional self-starter with a passion for science.
- Proven ability to work collaboratively with effective communication in a team environment as well as being an individual contributor.
- Direct, hands-on experience with adeno-associated viral nanoparticles.
- Experience operating chromatography methods (HPLC, etc.) and proficient understanding of chromatography software.
- Experience operating general ultracentrifugation methods.
- Experience operating PCR methods.
- Experience in analytical method development and assay transfer.
- Experience in statistical analysis with proficiency in statistical analysis software.
skills: PCR, Assay Development, Chromatography, High Pressure Liquid Chromatography (HPLC), Dynamic Light Scattering (DLS), Gel Electrophoresis (SDS-PAGE), Good Manufacturing Practices (GMP)
Equal Opportunity Employer: Race, Color, Religion, Sex, Sexual Orientation, Gender Identity, National Origin, Age, Genetic Information, Disability, Protected Veteran Status, or any other legally protected group status.
At Randstad, we welcome people of all abilities and want to ensure that our hiring and interview process meets the needs of all applicants. If you require a reasonable accommodation to make your application or interview experience a great one, please contact HRsupport@randstadusa.com.
Pay offered to a successful candidate will be based on several factors including the candidate's education, work experience, work location, specific job duties, certifications, etc. In addition, Randstad offers a comprehensive benefits package, including: medical, prescription, dental, vision, AD&D, and life insurance offerings, short-term disability, and a 401K plan (all benefits are based on eligibility).
This posting is open for thirty (30) days.
Qualified applicants in San Francisco with criminal histories will be considered for employment in accordance with the San Francisco Fair Chance Ordinance.
Qualified applicants with arrest or conviction records will be considered for employment in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
We will consider for employment all qualified Applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance.
